A two-step resin based approach to reveal survivin-selective fluorescent probes

The identification of modulators for proteins without assayable biochemical activity remains a challenge in chemical biology. The presented approach adapts a high-throughput fluorescence binding assay and functional chromatography, two protein-resin technologies, enabling the discovery and isolation...

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Detalles Bibliográficos
Autores principales: Ambrose, Andrew J., Pham, Nhan T., Sivinski, Jared, Guimarães, Larissa, Mollasalehi, Niloufar, Jimenez, Paula, Abad, Maria A., Jeyaprakash, A. Arockia, Shave, Steven, Costa-Lotufo, Letícia V., La Clair, James J., Auer, Manfred, Chapman, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342005/
https://www.ncbi.nlm.nih.gov/pubmed/34458780
http://dx.doi.org/10.1039/d0cb00122h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342005/
https://www.ncbi.nlm.nih.gov/pubmed/34458780
http://dx.doi.org/10.1039/d0cb00122h

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