Modeling alcohol-associated liver disease in a human Liver-Chip

Alcohol-associated liver disease (ALD) is a global health issue and leads to progressive liver injury, comorbidities, and increased mortality. Human-relevant preclinical models of ALD are urgently needed. Here, we leverage a triculture human Liver-Chip with biomimetic hepatic sinusoids and bile cana...

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Detalles Bibliográficos
Autores principales: Nawroth, Janna C., Petropolis, Debora B., Manatakis, Dimitris V., Maulana, Tengku Ibrahim, Burchett, Gabriel, Schlünder, Katharina, Witt, Anke, Shukla, Abhishek, Kodella, Konstantia, Ronxhi, Janey, Kulkarni, Gauri, Hamilton, Geraldine, Seki, Ekihiro, Lu, Shelly, Karalis, Katia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342038/
https://www.ncbi.nlm.nih.gov/pubmed/34289365
http://dx.doi.org/10.1016/j.celrep.2021.109393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342038/
https://www.ncbi.nlm.nih.gov/pubmed/34289365
http://dx.doi.org/10.1016/j.celrep.2021.109393

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