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Modeling alcohol-associated liver disease in a human Liver-Chip
Alcohol-associated liver disease (ALD) is a global health issue and leads to progressive liver injury, comorbidities, and increased mortality. Human-relevant preclinical models of ALD are urgently needed. Here, we leverage a triculture human Liver-Chip with biomimetic hepatic sinusoids and bile cana...
Autores principales: | Nawroth, Janna C., Petropolis, Debora B., Manatakis, Dimitris V., Maulana, Tengku Ibrahim, Burchett, Gabriel, Schlünder, Katharina, Witt, Anke, Shukla, Abhishek, Kodella, Konstantia, Ronxhi, Janey, Kulkarni, Gauri, Hamilton, Geraldine, Seki, Ekihiro, Lu, Shelly, Karalis, Katia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342038/ https://www.ncbi.nlm.nih.gov/pubmed/34289365 http://dx.doi.org/10.1016/j.celrep.2021.109393 |
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