Metformin Increases Protein Phosphatase 2A Activity in Primary Human Skeletal Muscle Cells Derived from Lean Healthy Participants

OBJECTIVE: To investigate if PP2A plays a role in metformin-induced insulin sensitivity improvement in human skeletal muscle cells. Participants. Eight lean insulin-sensitive nondiabetic participants (4 females and 4 males; age: 21.0 ± 1.0 years; BMI: 22.0 ± 0.7 kg/m(2); 2-hour OGTT: 97.0 ± 6.0 mg/d...

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Detalles Bibliográficos
Autores principales: Mestareehi, Aktham, Zhang, Xiangmin, Seyoum, Berhane, Msallaty, Zaher, Mallisho, Abdullah, Burghardt, Kyle Jon, Kowluru, Anjaneyulu, Yi, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342103/
https://www.ncbi.nlm.nih.gov/pubmed/34368369
http://dx.doi.org/10.1155/2021/9979234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342103/
https://www.ncbi.nlm.nih.gov/pubmed/34368369
http://dx.doi.org/10.1155/2021/9979234

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