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The PI3K pathway as a therapeutic intervention point in inflammatory bowel disease

With glucose being the preferred source of energy in activated T cells, targeting glycolysis has become an attractive therapeutic intervention point for chronic inflammatory bowel diseases (IBD). The switch to glycolysis is mediated by phosphoinositide‐3‐kinases (PI3K) which relay signals from surfa...

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Detalles Bibliográficos
Autores principales: Winkelmann, Paula, Unterweger, Anna‐Lena, Khullar, Diya, Beigel, Florian, Koletzko, Leandra, Siebeck, Matthias, Gropp, Roswitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342202/
https://www.ncbi.nlm.nih.gov/pubmed/33942546
http://dx.doi.org/10.1002/iid3.435