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The PI3K pathway as a therapeutic intervention point in inflammatory bowel disease
With glucose being the preferred source of energy in activated T cells, targeting glycolysis has become an attractive therapeutic intervention point for chronic inflammatory bowel diseases (IBD). The switch to glycolysis is mediated by phosphoinositide‐3‐kinases (PI3K) which relay signals from surfa...
Autores principales: | Winkelmann, Paula, Unterweger, Anna‐Lena, Khullar, Diya, Beigel, Florian, Koletzko, Leandra, Siebeck, Matthias, Gropp, Roswitha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342202/ https://www.ncbi.nlm.nih.gov/pubmed/33942546 http://dx.doi.org/10.1002/iid3.435 |
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