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IL‐13 modulates ∆Np63 levels causing altered expression of barrier‐ and inflammation‐related molecules in human keratinocytes: A possible explanation for chronicity of atopic dermatitis

BACKGROUND: Barrier disruption and an excessive immune response in keratinocytes are now considered to have important roles in the pathophysiology of atopic dermatitis (AD). Furthermore, disturbed keratinocyte differentiation is considered to underlie AD. ΔNp63, a p53‐like transcription factor, is a...

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Detalles Bibliográficos
Autores principales: Kubo, Terufumi, Sato, Sayuri, Hida, Tokimasa, Minowa, Tomoyuki, Hirohashi, Yoshihiko, Tsukahara, Tomohide, Kanaseki, Takayuki, Murata, Kenji, Uhara, Hisashi, Torigoe, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342210/
https://www.ncbi.nlm.nih.gov/pubmed/33792188
http://dx.doi.org/10.1002/iid3.427