Cargando…
Rigosertib inhibits MEK1–ERK pathway and alleviates lipopolysaccharide‐induced sepsis
BACKGROUND: Here, by using the lipopolysaccharide (LPS)‐induced mice sepsis model, we treated septic wild‐type (WT) mice or MEK1(DD) mice with rigosertib to evaluate its prospective effects on sepsis. METHODS: We also generated macrophages derived from bone marrow from WT or MEK1(DD) mice. These mac...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342218/ https://www.ncbi.nlm.nih.gov/pubmed/34061465 http://dx.doi.org/10.1002/iid3.458 |