The complex role of AIM2 in autoimmune diseases and cancers

Absent in melanoma 2 (AIM2) is a novel member of interferon (IFN)‐inducible PYHIN proteins. In innate immune cells, AIM2 servers as a cytoplasmic double‐stranded DNA sensor, playing a crucial role in the initiation of the innate immune response as a component of the inflammasome. AIM2 expression is...

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Detalles Bibliográficos
Autores principales: Zhu, Huan, Zhao, Ming, Chang, Christopher, Chan, Vera, Lu, Qianjin, Wu, Haijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342223/
https://www.ncbi.nlm.nih.gov/pubmed/34014039
http://dx.doi.org/10.1002/iid3.443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342223/
https://www.ncbi.nlm.nih.gov/pubmed/34014039
http://dx.doi.org/10.1002/iid3.443

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