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The complex role of AIM2 in autoimmune diseases and cancers

Absent in melanoma 2 (AIM2) is a novel member of interferon (IFN)‐inducible PYHIN proteins. In innate immune cells, AIM2 servers as a cytoplasmic double‐stranded DNA sensor, playing a crucial role in the initiation of the innate immune response as a component of the inflammasome. AIM2 expression is...

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Detalles Bibliográficos
Autores principales:	Zhu, Huan, Zhao, Ming, Chang, Christopher, Chan, Vera, Lu, Qianjin, Wu, Haijing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342223/ https://www.ncbi.nlm.nih.gov/pubmed/34014039 http://dx.doi.org/10.1002/iid3.443

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