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Ferulic acid suppresses interleukin‐1β‐induced degeneration of chondrocytes isolated from patients with osteoarthritis through the SIRT1/AMPK/PGC‐1α signaling pathway

BACKGROUND: Interleukin‐1β (IL‐1β) is involved in osteoarthritis pathogenesis and mediates a series of toxic processes including the production of matrix metalloproteinase and inflammatory regulators which are suppressed by activation of silent information regulator 1 (SIRT1). We aimed to determine...

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Detalles Bibliográficos
Autores principales: Du, Kewei, Fang, Xuchen, Li, Ziqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342228/
https://www.ncbi.nlm.nih.gov/pubmed/34078001
http://dx.doi.org/10.1002/iid3.424