Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer

Programmed cell death 1 (PD-1) is widely expressed in tumor-infiltrating lymphocytes (TILs) of triple-negative breast cancer (TNBC). As a dominant inhibitory immune checkpoint (ICP) receptor, cell surface PD-1 is well-known to transduce negative signaling of effector T cell activity during cell–cell...

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Detalles Bibliográficos
Autores principales: Qiu, Yufan, Yang, Yi, Yang, Riyao, Liu, Chunxiao, Hsu, Jung-Mao, Jiang, Zhou, Sun, Linlin, Wei, Yongkun, Li, Chia-Wei, Yu, Dihua, Zhang, Jin, Hung, Mien-Chie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342306/
https://www.ncbi.nlm.nih.gov/pubmed/34172932
http://dx.doi.org/10.1038/s41388-021-01896-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342306/
https://www.ncbi.nlm.nih.gov/pubmed/34172932
http://dx.doi.org/10.1038/s41388-021-01896-1

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