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Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer
Programmed cell death 1 (PD-1) is widely expressed in tumor-infiltrating lymphocytes (TILs) of triple-negative breast cancer (TNBC). As a dominant inhibitory immune checkpoint (ICP) receptor, cell surface PD-1 is well-known to transduce negative signaling of effector T cell activity during cell–cell...
Autores principales: | Qiu, Yufan, Yang, Yi, Yang, Riyao, Liu, Chunxiao, Hsu, Jung-Mao, Jiang, Zhou, Sun, Linlin, Wei, Yongkun, Li, Chia-Wei, Yu, Dihua, Zhang, Jin, Hung, Mien-Chie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342306/ https://www.ncbi.nlm.nih.gov/pubmed/34172932 http://dx.doi.org/10.1038/s41388-021-01896-1 |
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