Activation of autophagy reverses gemcitabine-induced immune inhibition of RAW264.7 macrophages by promoting TNF-α, IL-6 and MHC-II expression

This research aims to investigate the effect of gemcitabine (GEM) on various activities and functions of macrophages. Phagocytosis, cell autophagy and reactive oxygen species (ROS) were analysed by laser scanning confocal microscope. The cell cycle status and major histocompatibility complex II (MHC...

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Detalles Bibliográficos
Autores principales: Jiang, Shanshan, Wang, Rong, Han, Lu, Kuerban, Kudelaidi, Ye, Li, Pan, Shu, Li, Shengnan, Yuan, Yongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342359/
https://www.ncbi.nlm.nih.gov/pubmed/34259987
http://dx.doi.org/10.1007/s12026-021-09210-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342359/
https://www.ncbi.nlm.nih.gov/pubmed/34259987
http://dx.doi.org/10.1007/s12026-021-09210-7

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