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“Guilt by association” is not competitive with genetic association for identifying autism risk genes

Discovering genes involved in complex human genetic disorders is a major challenge. Many have suggested that machine learning (ML) algorithms using gene networks can be used to supplement traditional genetic association-based approaches to predict or prioritize disease genes. However, questions have...

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Detalles Bibliográficos
Autores principales: Gunning, Margot, Pavlidis, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342445/
https://www.ncbi.nlm.nih.gov/pubmed/34354131
http://dx.doi.org/10.1038/s41598-021-95321-y