Identification of transmissible proteotoxic oligomer-like fibrils that expand conformational diversity of amyloid assemblies

Protein misfolding and amyloid deposition are associated with numerous diseases. The detailed characterization of the proteospecies mediating cell death remains elusive owing to the (supra)structural polymorphism and transient nature of the assemblies populating the amyloid pathway. Here we describe...

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Detalles Bibliográficos
Autores principales: Nguyen, Phuong Trang, Zottig, Ximena, Sebastiao, Mathew, Arnold, Alexandre A., Marcotte, Isabelle, Bourgault, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342456/
https://www.ncbi.nlm.nih.gov/pubmed/34354242
http://dx.doi.org/10.1038/s42003-021-02466-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342456/
https://www.ncbi.nlm.nih.gov/pubmed/34354242
http://dx.doi.org/10.1038/s42003-021-02466-7

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