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Identification of transmissible proteotoxic oligomer-like fibrils that expand conformational diversity of amyloid assemblies
Protein misfolding and amyloid deposition are associated with numerous diseases. The detailed characterization of the proteospecies mediating cell death remains elusive owing to the (supra)structural polymorphism and transient nature of the assemblies populating the amyloid pathway. Here we describe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342456/ https://www.ncbi.nlm.nih.gov/pubmed/34354242 http://dx.doi.org/10.1038/s42003-021-02466-7 |