Investigating crosstalk between H3K27 acetylation and H3K4 trimethylation in CRISPR/dCas-based epigenome editing and gene activation

Epigenome editing methods enable the precise manipulation of epigenetic modifications, such as histone posttranscriptional modifications (PTMs), for uncovering their biological functions. While histone PTMs have been correlated with certain gene expression status, the causalities remain elusive. His...

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Detalles Bibliográficos
Autores principales: Zhao, Weiye, Xu, Ying, Wang, Yufan, Gao, Dan, King, Jasmine, Xu, Yajie, Liang, Fu-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342468/
https://www.ncbi.nlm.nih.gov/pubmed/34354157
http://dx.doi.org/10.1038/s41598-021-95398-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342468/
https://www.ncbi.nlm.nih.gov/pubmed/34354157
http://dx.doi.org/10.1038/s41598-021-95398-5

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