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Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro model to recapitulate human brain development and neurological diseases. However, the current systems for brain organoid culture require further improvement for the reliable production of high-quality organo...

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Detalles Bibliográficos
Autores principales: Cho, Ann-Na, Jin, Yoonhee, An, Yeonjoo, Kim, Jin, Choi, Yi Sun, Lee, Jung Seung, Kim, Junghoon, Choi, Won-Young, Koo, Dong-Jun, Yu, Weonjin, Chang, Gyeong-Eon, Kim, Dong-Yoon, Jo, Sung-Hyun, Kim, Jihun, Kim, Sung-Yon, Kim, Yun-Gon, Kim, Ju Young, Choi, Nakwon, Cheong, Eunji, Kim, Young-Joon, Je, Hyunsoo Shawn, Kang, Hoon-Chul, Cho, Seung-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342542/
https://www.ncbi.nlm.nih.gov/pubmed/34354063
http://dx.doi.org/10.1038/s41467-021-24775-5