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Rhodaelectro-catalyzed access to chromones via formyl C–H activation towards peptide electro-labeling

Chromones represent a privileged scaffold in medicinal chemistry and are an omnipresent structural motif in natural products. Chemically encoded non-natural peptidomimetics feature improved stability towards enzymatic degradation, cell permeability and binding affinity, translating into a considerab...

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Detalles Bibliográficos
Autores principales: Stangier, Maximilian, Messinis, Antonis M., Oliveira, João C. A., Yu, Hao, Ackermann, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342597/
https://www.ncbi.nlm.nih.gov/pubmed/34354056
http://dx.doi.org/10.1038/s41467-021-25005-8