Cargando…

Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment

The tumor microenvironment (TME) is a complex amalgam of tumor cells, immune cells, endothelial cells and fibroblastic stromal cells (FSC). Cancer-associated fibroblasts are generally seen as tumor-promoting entity. However, it is conceivable that particular FSC populations within the TME contribute...

Descripción completa

Detalles Bibliográficos
Autores principales: Ring, Sandra S., Cupovic, Jovana, Onder, Lucas, Lütge, Mechthild, Perez-Shibayama, Christian, Gil-Cruz, Cristina, Scandella, Elke, De Martin, Angelina, Mörbe, Urs, Hartmann, Fabienne, Wenger, Robert, Spiegl, Matthias, Besse, Andrej, Bonilla, Weldy V., Stemeseder, Felix, Schmidt, Sarah, Orlinger, Klaus K., Krebs, Philippe, Ludewig, Burkhard, Flatz, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342618/
https://www.ncbi.nlm.nih.gov/pubmed/34354077
http://dx.doi.org/10.1038/s41467-021-25057-w