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Hydrogen sulfide stimulates lipid biogenesis from glutamine that is dependent on the mitochondrial NAD(P)H pool

Mammalian cells synthesize H(2)S from sulfur-containing amino acids and are also exposed to exogenous sources of this signaling molecule, notably from gut microbes. As an inhibitor of complex IV in the electron transport chain, H(2)S can have a profound impact on metabolism, suggesting the hypothesi...

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Detalles Bibliográficos
Autores principales: Carballal, Sebastian, Vitvitsky, Victor, Kumar, Roshan, Hanna, David A., Libiad, Marouane, Gupta, Aditi, Jones, Jace W., Banerjee, Ruma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342795/
https://www.ncbi.nlm.nih.gov/pubmed/34252456
http://dx.doi.org/10.1016/j.jbc.2021.100950