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Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection

BACKGROUND: SARS-CoV-2 infection is associated with thrombotic and microvascular complications. The cause of coagulopathy in the disease is incompletely understood. METHODS: A single-center cross-sectional study including 66 adult COVID-19 patients (40 moderate, 26 severe disease), and 9 controls, p...

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Detalles Bibliográficos
Autores principales: Francischetti, Ivo M.B., Toomer, Kevin, Zhang, Yifan, Jani, Jayesh, Siddiqui, Zishan, Brotman, Daniel J., Hooper, Jody E., Kickler, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342934/
https://www.ncbi.nlm.nih.gov/pubmed/34377969
http://dx.doi.org/10.1016/j.eclinm.2021.101069