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Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet

BACKGROUND & AIMS: How benign liver steatosis progresses to nonalcoholic steatohepatitis (NASH), fibrosis, and hepatocellular carcinoma (HCC) remains elusive. NASH progression entails diverse pathogenic mechanisms and relies on complex cross-talk between multiple tissues such as the gut, adipose...

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Detalles Bibliográficos
Autores principales: Ganguly, Souradipta, Muench, German Aleman, Shang, Linshan, Rosenthal, Sara Brin, Rahman, Gibraan, Wang, Ruoyu, Wang, Yanhan, Kwon, Hyeok Choon, Diomino, Anthony M., Kisseleva, Tatiana, Soorosh, Pejman, Hosseini, Mojgan, Knight, Rob, Schnabl, Bernd, Brenner, David A., Dhar, Debanjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342972/
https://www.ncbi.nlm.nih.gov/pubmed/34062281
http://dx.doi.org/10.1016/j.jcmgh.2021.05.010