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Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet
BACKGROUND & AIMS: How benign liver steatosis progresses to nonalcoholic steatohepatitis (NASH), fibrosis, and hepatocellular carcinoma (HCC) remains elusive. NASH progression entails diverse pathogenic mechanisms and relies on complex cross-talk between multiple tissues such as the gut, adipose...
Autores principales: | Ganguly, Souradipta, Muench, German Aleman, Shang, Linshan, Rosenthal, Sara Brin, Rahman, Gibraan, Wang, Ruoyu, Wang, Yanhan, Kwon, Hyeok Choon, Diomino, Anthony M., Kisseleva, Tatiana, Soorosh, Pejman, Hosseini, Mojgan, Knight, Rob, Schnabl, Bernd, Brenner, David A., Dhar, Debanjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342972/ https://www.ncbi.nlm.nih.gov/pubmed/34062281 http://dx.doi.org/10.1016/j.jcmgh.2021.05.010 |
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