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Mesoscopic Mapping of Ictal Neurovascular Coupling in Awake Behaving Mice Using Optical Spectroscopy and Genetically Encoded Calcium Indicators

Unambiguously identifying an epileptic focus with high spatial resolution is a challenge, especially when no anatomic abnormality can be detected. Neurovascular coupling (NVC)-based brain mapping techniques are often applied in the clinic despite a poor understanding of ictal NVC mechanisms, derived...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Li, Jing, Song, Yan, Zhao, Mingrui, Niemeyer, James E., Luo, Peijuan, Li, Dan, Lin, Weihong, Ma, Hongtao, Schwartz, Theodore H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343016/
https://www.ncbi.nlm.nih.gov/pubmed/34366781
http://dx.doi.org/10.3389/fnins.2021.704834