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Pharmacologically targeting molecular motor promotes mitochondrial fission for anti-cancer

Mitochondrial shape rapidly changes by dynamic balance of fusion and fission to adjust to constantly changing energy demands of cancer cells. Mitochondrial dynamics balance is exactly regulated by molecular motor consisted of myosin and actin cytoskeleton proteins. Thus, targeting myosin–actin molec...

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Detalles Bibliográficos
Autores principales: Qian, Yi, Zhao, Meimei, Han, Qinghua, Wang, Jingkang, Liao, Lixi, Yang, Heng, Liu, Dan, Tu, Pengfei, Liang, Hong, Zeng, Kewu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343112/
https://www.ncbi.nlm.nih.gov/pubmed/34386324
http://dx.doi.org/10.1016/j.apsb.2021.01.011