Cargando…

Molecularly engineered truncated tissue factor with therapeutic aptamers for tumor-targeted delivery and vascular infarction

Selective occlusion of tumor vasculature has proven to be an effective strategy for cancer therapy. Among vascular coagulation agents, the extracellular domain of coagulation-inducing protein tissue factor, truncated tissue factor (tTF), is the most widely used. Since the truncated protein exhibits...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Bozhao, Wei, Jingyan, Di, Chunzhi, Lu, Zefang, Qi, Feilong, Zhang, Yinlong, Leong, Wei Sun, Li, Lele, Nie, Guangjun, Li, Suping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343113/
https://www.ncbi.nlm.nih.gov/pubmed/34386338
http://dx.doi.org/10.1016/j.apsb.2020.11.014