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Molecularly engineered truncated tissue factor with therapeutic aptamers for tumor-targeted delivery and vascular infarction
Selective occlusion of tumor vasculature has proven to be an effective strategy for cancer therapy. Among vascular coagulation agents, the extracellular domain of coagulation-inducing protein tissue factor, truncated tissue factor (tTF), is the most widely used. Since the truncated protein exhibits...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343113/ https://www.ncbi.nlm.nih.gov/pubmed/34386338 http://dx.doi.org/10.1016/j.apsb.2020.11.014 |