In situ triggering antitumor efficacy of alcohol-abuse drug disulfiram through Cu-based metal-organic framework nanoparticles

Although approved as an alcohol-abuse drug, disulfiram (DSF) exhibited potential anticancer activity when chelated with copper (Cu). However, the low level of intrinsic Cu, toxicity originated from exogenous Cu supplementation, and poor stability of DSF in vivo severely limited its application in ca...

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Detalles Bibliográficos
Autores principales: Hou, Lin, Liu, Yanlong, Liu, Wei, Balash, Mervat, Zhang, Hongling, Zhang, Yi, Zhang, Huijuan, Zhang, Zhenzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343114/
https://www.ncbi.nlm.nih.gov/pubmed/34386335
http://dx.doi.org/10.1016/j.apsb.2021.01.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343114/
https://www.ncbi.nlm.nih.gov/pubmed/34386335
http://dx.doi.org/10.1016/j.apsb.2021.01.013

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