Inhibition of LIM kinase reduces contraction and proliferation in bladder smooth muscle

Overactive bladder (OAB) is the most bothersome symptom in lower urinary tract symptoms (LUTS). Current pharmacologic treatment aims to inhibit detrusor contraction; however, shows unsatisfied efficacy and high discontinuation rate. LIM kinases (LIMKs) promote smooth muscle contraction in the prosta...

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Detalles Bibliográficos
Autores principales: Yu, Qingfeng, Wu, Chengjie, Chen, Yeda, Li, Bingsheng, Wang, Ruixiao, Huang, Ru, Li, Xuechun, Gu, Di, Wang, Xiaolong, Duan, Xiaolu, Li, Shujue, Liu, Yang, Wu, Wenqi, Hennenberg, Martin, Zeng, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343115/
https://www.ncbi.nlm.nih.gov/pubmed/34386328
http://dx.doi.org/10.1016/j.apsb.2021.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343115/
https://www.ncbi.nlm.nih.gov/pubmed/34386328
http://dx.doi.org/10.1016/j.apsb.2021.01.005

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