A novel PGAM5 inhibitor LFHP-1c protects blood–brain barrier integrity in ischemic stroke

Blood–brain barrier (BBB) damage after ischemia significantly influences stroke outcome. Compound LFHP-1c was previously discovered with neuroprotective role in stroke model, but its mechanism of action on protection of BBB disruption after stroke remains unknown. Here, we show that LFHP-1c, as a di...

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Detalles Bibliográficos
Autores principales: Gao, Chenglong, Xu, Yazhou, Liang, Zhuangzhuang, Wang, Yunjie, Shang, Qinghong, Zhang, Shengbin, Wang, Cunfang, Ni, Mingmin, Wu, Dalei, Huang, Zhangjian, Pang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343116/
https://www.ncbi.nlm.nih.gov/pubmed/34386325
http://dx.doi.org/10.1016/j.apsb.2021.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343116/
https://www.ncbi.nlm.nih.gov/pubmed/34386325
http://dx.doi.org/10.1016/j.apsb.2021.01.008

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