Analysis of Diffusion Tensor Imaging Data From the UK Biobank Confirms Dosage Effect of 15q11.2 Copy Number Variation on White Matter and Shows Association With Cognition

BACKGROUND: Copy number variations at the 15q11.2 BP1-BP2 locus are present in 0.5%–1.0% of the population, and the deletion is associated with several neurodevelopmental disorders. Previously, we showed a reciprocal effect of 15q11.2 copy number variation on fractional anisotropy, with widespread i...

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Detalles Bibliográficos
Autores principales: Silva, Ana I., Kirov, George, Kendall, Kimberley M., Bracher-Smith, Mathew, Wilkinson, Lawrence S., Hall, Jeremy, Ulfarsson, Magnus O., Walters, G. Bragi, Stefansson, Hreinn, Stefansson, Kari, Linden, David E.J., Caseras, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343146/
https://www.ncbi.nlm.nih.gov/pubmed/33931204
http://dx.doi.org/10.1016/j.biopsych.2021.02.969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343146/
https://www.ncbi.nlm.nih.gov/pubmed/33931204
http://dx.doi.org/10.1016/j.biopsych.2021.02.969

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