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Construction of Mode of Action for Cadmium-Induced Renal Tubular Dysfunction Based on a Toxicity Pathway-Oriented Approach

Although it is recognized that cadmium (Cd) causes renal tubular dysfunction, the mechanism of Cd-induced nephrotoxicity is not yet fully understood. Mode of action (MOA) is a developing tool for chemical risk assessment. To establish the mechanistic MOA of Cd-induced renal tubular dysfunction, the...

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Detalles Bibliográficos
Autores principales: Zhang, Yangchun, Liu, Ziqi, He, Qianmei, Wu, Fei, Xiao, Yongmei, Chen, Wen, Jin, Yuan, Yu, Dianke, Wang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343180/
https://www.ncbi.nlm.nih.gov/pubmed/34367254
http://dx.doi.org/10.3389/fgene.2021.696892