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Pure redox-sensitive paclitaxel–maleimide prodrug nanoparticles: Endogenous albumin-induced size switching and improved antitumor efficiency

A commercial albumin-bound paclitaxel nano-formulation has been considered a gold standard against breast cancer. However, its application still restricted unfavorable pharmacokinetics and the immunogenicity of exogenous albumin carrier. Herein, we report an albumin-bound tumor redox-responsive pacl...

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Detalles Bibliográficos
Autores principales: Lou, Xinyu, Zhang, Dong, Ling, Hao, He, Zhonggui, Sun, Jin, Sun, Mengchi, Liu, Dongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343193/
https://www.ncbi.nlm.nih.gov/pubmed/34386337
http://dx.doi.org/10.1016/j.apsb.2020.12.001