Cargando…

Stevens-Johnson syndrome/toxic epidermal necrolysis in patients treated with immune checkpoint inhibitors: A safety analysis of clinical trials and FDA pharmacovigilance database

BACKGROUND: The association between immune checkpoint inhibitors (ICIs) and Stevens-Johnsons syndrome (SJS) /toxic epidermal necrolysis (TEN) is unclear. We assessed the risk of SJS and TEN related to ICIs, via a systematic analysis of SJS/TEN cases reported in clinical trials and the FDA Adverse Ev...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Jianhong, Chen, Guanghui, He, Zhichao, Zheng, Yayuan, Gao, Siyuan, Li, Jianfang, Ling, Yin, Yu, Xiaoxia, Qiu, Kaifeng, Wu, Junyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343267/
https://www.ncbi.nlm.nih.gov/pubmed/34386743
http://dx.doi.org/10.1016/j.eclinm.2021.100951