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Sorbitol and PKC1 overexpression alleviate temperature sensitivity in chaperonin mutants of Saccharomyces cerevisiae

CCT (Chaperonin containing TCP-1) is a constitutively expressed eukaryotic chaperonin complex involved in the proper folding of proteins like actin and tubulin. Temperature sensitive mutants of CCT complex have been employed in various genetic screens, acting as models to study human CCT, the defect...

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Detalles Bibliográficos
Autores principales: Narayanan, Aswathy, Kabir, M. Anaul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343407/
https://www.ncbi.nlm.nih.gov/pubmed/34377964
http://dx.doi.org/10.17912/micropub.biology.000440