Effect of 5-aza-2ˈ-deoxycytidine on p27Kip1, p21Cip1/Waf1/Sdi1, p57Kip2, and DNA methyltransferase 1 Genes Expression, Cell Growth Inhibition and Apoptosis Induction in Colon Cancer SW 480 and SW 948 Cell Lines

BACKGROUND: Dysregulation of the cell cycle has been reported in various cancers. Inactivation of the cyclin-dependent kinases inhibitors (CDKIs), CIP/KIP family, such as p21Cip1/Waf1/Sdi1, p27Kip1, and p57Kip2 genes because of hypermethylation has been shown in several cancers. Treatment with DNA d...

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Detalles Bibliográficos
Autores principales: Sanaei, Masumeh, Kavoosi, Fraidoon, Nasiri, Sedighe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Salvia Medical Sciences Ltd 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343479/
https://www.ncbi.nlm.nih.gov/pubmed/34466608
http://dx.doi.org/10.31661/gmj.v9i0.1899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343479/
https://www.ncbi.nlm.nih.gov/pubmed/34466608
http://dx.doi.org/10.31661/gmj.v9i0.1899

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