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Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle
Abnormal deposition of misfolded proteins is a neuropathological characteristic shared by many neurodegenerative disorders including Alzheimer’s disease (AD). Generation of excessive amounts of aggregated proteins and impairment of degradation systems for misfolded proteins such as autophagy can lea...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Salvia Medical Sciences Ltd
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343705/ https://www.ncbi.nlm.nih.gov/pubmed/34466566 http://dx.doi.org/10.31661/gmj.v9i0.1681 |