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Lidocaine liposome modified with folic acid suppresses the proliferation and motility of glioma cells via targeting the PI3K/AKT pathway

Glioma is life-threatening tumor of the central nervous system. Although lidocaine is usually used as local anesthetic, it also has antitumor effects. However, its clinical application in glioma is hampered by limited distribution to the brain. The aim of the present study was to enhance the ability...

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Detalles Bibliográficos
Autores principales: Li, Dedong, Yang, Xuewei, Li, Bo, Yang, Chenyi, Sun, Jian, Yu, Mingdong, Wang, Haiyun, Lu, Yuechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343891/
https://www.ncbi.nlm.nih.gov/pubmed/34373711
http://dx.doi.org/10.3892/etm.2021.10457