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Lidocaine liposome modified with folic acid suppresses the proliferation and motility of glioma cells via targeting the PI3K/AKT pathway
Glioma is life-threatening tumor of the central nervous system. Although lidocaine is usually used as local anesthetic, it also has antitumor effects. However, its clinical application in glioma is hampered by limited distribution to the brain. The aim of the present study was to enhance the ability...
Autores principales: | Li, Dedong, Yang, Xuewei, Li, Bo, Yang, Chenyi, Sun, Jian, Yu, Mingdong, Wang, Haiyun, Lu, Yuechun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343891/ https://www.ncbi.nlm.nih.gov/pubmed/34373711 http://dx.doi.org/10.3892/etm.2021.10457 |
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