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Biomimetic nerve guidance conduit containing engineered exosomes of adipose-derived stem cells promotes peripheral nerve regeneration

BACKGROUND: Efficient and stable delivery of neurotrophic factors (NTFs) is crucial to provide suitable microenvironment for peripheral nerve regeneration. Neurotrophin-3 (NT-3) is an important NTF during peripheral nerve regeneration which is scarce in the first few weeks of nerve defect. Exosomes...

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Detalles Bibliográficos
Autores principales: Yang, Zheng, Yang, Yang, Xu, Yichi, Jiang, Weiqian, Shao, Yan, Xing, Jiahua, Chen, Youbai, Han, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343914/
https://www.ncbi.nlm.nih.gov/pubmed/34362437
http://dx.doi.org/10.1186/s13287-021-02528-x