Optimizing gentamicin dosing in different pediatric age groups using population pharmacokinetics and Monte Carlo simulation

INTRODUCTION: The use of once daily dosing of aminoglycosides in pediatrics is increasing but studies on dose optimization targeting the pediatric population are limited. This study aimed to derive a population pharmacokinetic model of gentamicin and apply it to design optimal dosing regimens in ped...

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Detalles Bibliográficos
Autores principales: Ghoneim, Ragia H., Thabit, Abrar K., Lashkar, Manar O., Ali, Ahmed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343923/
https://www.ncbi.nlm.nih.gov/pubmed/34362436
http://dx.doi.org/10.1186/s13052-021-01114-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343923/
https://www.ncbi.nlm.nih.gov/pubmed/34362436
http://dx.doi.org/10.1186/s13052-021-01114-4

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