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Optimizing gentamicin dosing in different pediatric age groups using population pharmacokinetics and Monte Carlo simulation
INTRODUCTION: The use of once daily dosing of aminoglycosides in pediatrics is increasing but studies on dose optimization targeting the pediatric population are limited. This study aimed to derive a population pharmacokinetic model of gentamicin and apply it to design optimal dosing regimens in ped...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343923/ https://www.ncbi.nlm.nih.gov/pubmed/34362436 http://dx.doi.org/10.1186/s13052-021-01114-4 |