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Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4

Rationale: The molecular mechanisms underlying the pathogenesis of systemic insulin resistance in type 2 diabetes remain elusive. Growth hormone receptor (GHR) deficiency has long been known to improved insulin sensitivity. However, whether hepatic GHR overexpression or activation is a cause of insu...

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Detalles Bibliográficos
Autores principales: Liu, Jinxin, Nie, Chenzhipeng, Xue, Lamei, Yan, Ying, Liu, Shengnan, Sun, Juan, Fan, Mingcong, Qian, Haifeng, Ying, Hao, Wang, Li, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344001/
https://www.ncbi.nlm.nih.gov/pubmed/34373742
http://dx.doi.org/10.7150/thno.61192