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Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling

Rationale: Optic neuritis is one of main symptoms in multiple sclerosis (MS) that causes visual disability. Astrocytes are pivotal regulators of neuroinflammation in MS, and astrocytic yes-associated protein (YAP) plays a critical role in neuroinflammation. Meanwhile, YAP signaling is involved in vi...

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Detalles Bibliográficos
Autores principales: Wu, Qian, Miao, Xuemeng, Zhang, Jingjing, Xiang, Ludan, Li, Xiuchun, Bao, Xiaomei, Du, Siyu, Wang, Mianxian, Miao, Shuangda, Fan, Yiren, Wang, Wei, Xu, Xingxing, Shen, Xiya, Yang, Danlu, Wang, Xiwu, Fang, Yuanyuan, Hu, Lixin, Pan, Xuyi, Dong, Haoru, Wang, Hui, Wang, Ying, Li, Jia, Huang, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344002/
https://www.ncbi.nlm.nih.gov/pubmed/34373754
http://dx.doi.org/10.7150/thno.60031