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Mitochondria-targeted and ultrasound-responsive nanoparticles for oxygen and nitric oxide codelivery to reverse immunosuppression and enhance sonodynamic therapy for immune activation

Background: Sonodynamic therapy (SDT) is a promising strategy to inhibit tumor growth and activate antitumor immune responses for immunotherapy. However, the hypoxic and immunosuppressive tumor microenvironment limits its therapeutic efficacy and suppresses immune response. Methods: In this study, m...

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Detalles Bibliográficos
Autores principales: Ji, Changwei, Si, Jingxing, Xu, Yan, Zhang, Wenjing, Yang, Yaqian, He, Xin, Xu, Hao, Mou, Xiaozhou, Ren, Hao, Guo, Hongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344010/
https://www.ncbi.nlm.nih.gov/pubmed/34373760
http://dx.doi.org/10.7150/thno.62572