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GATA3 functions downstream of BRCA1 to suppress EMT in breast cancer

Purpose: Functional loss of BRCA1 is associated with poorly differentiated and metastatic breast cancers that are enriched with cancer stem cells (CSCs). CSCs can be generated from carcinoma cells through an epithelial-mesenchymal transition (EMT) program. We and others have previously demonstrated...

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Detalles Bibliográficos
Autores principales: Bai, Feng, Zhang, Li-Han, Liu, Xiong, Wang, Chuying, Zheng, Chenglong, Sun, Jianping, Li, Min, Zhu, Wei-Guo, Pei, Xin-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344017/
https://www.ncbi.nlm.nih.gov/pubmed/34373738
http://dx.doi.org/10.7150/thno.59280