Discovery of Small Molecule Bak Activator for Lung Cancer Therapy

Rationale: Bak is a major proapoptotic Bcl2 family member and a required molecule for apoptotic cell death. High levels of endogenous Bak were observed in both small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) cell lines. Increased Bak expression was correlated with poor prognosis...

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Detalles Bibliográficos
Autores principales: Park, Dongkyoo, Anisuzzaman, Abu Syed Md, Magis, Andrew T., Chen, Guo, Xie, Maohua, Zhang, Guojing, Behera, Madhusmita, Sica, Gabriel L., Ramalingam, Suresh S., Owonikoko, Taofeek K., Deng, Xingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344021/
https://www.ncbi.nlm.nih.gov/pubmed/34373755
http://dx.doi.org/10.7150/thno.60349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344021/
https://www.ncbi.nlm.nih.gov/pubmed/34373755
http://dx.doi.org/10.7150/thno.60349

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