Establishment and characterization of patient-derived head and neck cancer models from surgical specimens and endoscopic biopsies

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is heterogeneous in etiology, phenotype and biology. Patient-derived xenografts (PDX) maintain morphology and molecular profiling of the original tumors and have become a standard “Avatar” model for human cancer research. However, restricted...

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Detalles Bibliográficos
Autores principales: Strüder, Daniel, Momper, Theresa, Irmscher, Nina, Krause, Mareike, Liese, Jan, Schraven, Sebastian, Zimpfer, Annette, Zonnur, Sarah, Burmeister, Ann-Sophie, Schneider, Björn, Frerich, Bernhard, Mlynski, Robert, Große-Thie, Christina, Junghanss, Christian, Maletzki, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344210/
https://www.ncbi.nlm.nih.gov/pubmed/34362423
http://dx.doi.org/10.1186/s13046-021-02047-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344210/
https://www.ncbi.nlm.nih.gov/pubmed/34362423
http://dx.doi.org/10.1186/s13046-021-02047-w

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