Inhibition of autophagy by CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR pathway contributes to ischemic postconditioning-induced neuroprotection against cerebral ischemia-reperfusion injury

Cerebral ischemia, a common cerebrovascular disease, is characterized by functional deficits and apoptotic cell death. Autophagy, a type of programmed cell death, plays critical roles in controlling neuronal damage and metabolic homeostasis, and has been inextricably linked to cerebral ischemia. We...

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Detalles Bibliográficos
Autores principales: Yao, Yuan, Ji, Yingshi, Ren, Jinghong, Liu, Huanyu, Khanna, Rajesh, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344221/
https://www.ncbi.nlm.nih.gov/pubmed/34362425
http://dx.doi.org/10.1186/s13041-021-00836-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344221/
https://www.ncbi.nlm.nih.gov/pubmed/34362425
http://dx.doi.org/10.1186/s13041-021-00836-0

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